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human adamts13 duoset elisa kit  (R&D Systems)


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    Structured Review

    R&D Systems human adamts13 duoset elisa kit
    Diagrams depicting the structures of <t>ADAMTS13,</t> MDTCS, and MDTCS-Fc. The MDTCS fragment is a truncated form of ADMTS13 and consists of the M, D, T1, C, and S domains essential to cleave vWF multimers. MDTCS-Fc consists of MDTCS, an IgG1 type hinge, and an IgG4 type Fc harboring YTE mutations to improve the FcRn binding affinity. M: metalloprotease domain, D: disintegrin-like domain, T1: the first thrombospondin type 1 repeat, C: Cys-rich domain, S: spacer domain, T2-8: the second to eighth TSP1 repeats, CUB: Complement c1r/c1s, sea Urchin epidermal growth factor, and bone morphogenetic protein, Fc: Fragment crystallizable.
    Human Adamts13 Duoset Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+adamts13+duoset+elisa+kit/Human+ADAMTS13+DuoSet+ELISA/pmc10999626-53-1-6
    Average 92 stars, based on 2 article reviews
    human adamts13 duoset elisa kit - by Bioz Stars, 2026-11
    92/100 stars

    Images

    1) Product Images from "Kinetic modeling of the plasma pharmacokinetic profiles of ADAMTS13 fragment and its Fc-fusion counterpart in mice"

    Article Title: Kinetic modeling of the plasma pharmacokinetic profiles of ADAMTS13 fragment and its Fc-fusion counterpart in mice

    Journal: Frontiers in Pharmacology

    doi: 10.3389/fphar.2024.1352842

    Diagrams depicting the structures of ADAMTS13, MDTCS, and MDTCS-Fc. The MDTCS fragment is a truncated form of ADMTS13 and consists of the M, D, T1, C, and S domains essential to cleave vWF multimers. MDTCS-Fc consists of MDTCS, an IgG1 type hinge, and an IgG4 type Fc harboring YTE mutations to improve the FcRn binding affinity. M: metalloprotease domain, D: disintegrin-like domain, T1: the first thrombospondin type 1 repeat, C: Cys-rich domain, S: spacer domain, T2-8: the second to eighth TSP1 repeats, CUB: Complement c1r/c1s, sea Urchin epidermal growth factor, and bone morphogenetic protein, Fc: Fragment crystallizable.
    Figure Legend Snippet: Diagrams depicting the structures of ADAMTS13, MDTCS, and MDTCS-Fc. The MDTCS fragment is a truncated form of ADMTS13 and consists of the M, D, T1, C, and S domains essential to cleave vWF multimers. MDTCS-Fc consists of MDTCS, an IgG1 type hinge, and an IgG4 type Fc harboring YTE mutations to improve the FcRn binding affinity. M: metalloprotease domain, D: disintegrin-like domain, T1: the first thrombospondin type 1 repeat, C: Cys-rich domain, S: spacer domain, T2-8: the second to eighth TSP1 repeats, CUB: Complement c1r/c1s, sea Urchin epidermal growth factor, and bone morphogenetic protein, Fc: Fragment crystallizable.

    Techniques Used: Binding Assay

    Related Articles

    Enzyme-linked Immunosorbent Assay:

    Article Title: Kinetic modeling of the plasma pharmacokinetic profiles of ADAMTS13 fragment and its Fc-fusion counterpart in mice
    Article Snippet: MDTCS and MDTCS-Fc were produced in Chinese hamster ovary (CHO) cells by a serum-free cell culture method (GC Biopharma, Republic of Korea) and their respective activity was measured with TECHNOZYM ® ADAMTS13 activity enzyme-linked immunosorbent assay (ELISA) kit (Technoclone Herstellung von Diagnostika und Arzneimitteln GmbH, Vienna, Austria) following the recommended protocol. .. A human ADAMTS13 DuoSet ELISA kit (R&D systems, Minneapolis, United States) was used to measure the concentrations of MDTCS or MDTCS-Fc in the plasma samples collected from the mice receiving MDTCS or MDTCS-Fc. .. The 96-well plates [Enzyme Immunoassay/Radioimmunoassay (EIA/RIA) plate or Greiner 96 well plate] were from Merck KGaA (Darmstadt, Germany) and 1-StepTM Ultra 3,3′,5,5′-Tetramethylbenzidine (TMB)-ELISA Substrate Solution was from Thermo Scientific (Massachusetts, United States).

    Clinical Proteomics:

    Article Title: Kinetic modeling of the plasma pharmacokinetic profiles of ADAMTS13 fragment and its Fc-fusion counterpart in mice
    Article Snippet: MDTCS and MDTCS-Fc were produced in Chinese hamster ovary (CHO) cells by a serum-free cell culture method (GC Biopharma, Republic of Korea) and their respective activity was measured with TECHNOZYM ® ADAMTS13 activity enzyme-linked immunosorbent assay (ELISA) kit (Technoclone Herstellung von Diagnostika und Arzneimitteln GmbH, Vienna, Austria) following the recommended protocol. .. A human ADAMTS13 DuoSet ELISA kit (R&D systems, Minneapolis, United States) was used to measure the concentrations of MDTCS or MDTCS-Fc in the plasma samples collected from the mice receiving MDTCS or MDTCS-Fc. .. The 96-well plates [Enzyme Immunoassay/Radioimmunoassay (EIA/RIA) plate or Greiner 96 well plate] were from Merck KGaA (Darmstadt, Germany) and 1-StepTM Ultra 3,3′,5,5′-Tetramethylbenzidine (TMB)-ELISA Substrate Solution was from Thermo Scientific (Massachusetts, United States).



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    human adamts13 duoset elisa kit  (R&D Systems)
    92
    R&D Systems human adamts13 duoset elisa kit
    Diagrams depicting the structures of <t>ADAMTS13,</t> MDTCS, and MDTCS-Fc. The MDTCS fragment is a truncated form of ADMTS13 and consists of the M, D, T1, C, and S domains essential to cleave vWF multimers. MDTCS-Fc consists of MDTCS, an IgG1 type hinge, and an IgG4 type Fc harboring YTE mutations to improve the FcRn binding affinity. M: metalloprotease domain, D: disintegrin-like domain, T1: the first thrombospondin type 1 repeat, C: Cys-rich domain, S: spacer domain, T2-8: the second to eighth TSP1 repeats, CUB: Complement c1r/c1s, sea Urchin epidermal growth factor, and bone morphogenetic protein, Fc: Fragment crystallizable.
    Human Adamts13 Duoset Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+adamts13+duoset+elisa+kit/Human+ADAMTS13+DuoSet+ELISA/pmc10999626-53-1-6
    Average 92 stars, based on 1 article reviews
    human adamts13 duoset elisa kit - by Bioz Stars, 2026-11
    92/100 stars
    		  Buy from Supplier

    Image Search Results


    Diagrams depicting the structures of ADAMTS13, MDTCS, and MDTCS-Fc. The MDTCS fragment is a truncated form of ADMTS13 and consists of the M, D, T1, C, and S domains essential to cleave vWF multimers. MDTCS-Fc consists of MDTCS, an IgG1 type hinge, and an IgG4 type Fc harboring YTE mutations to improve the FcRn binding affinity. M: metalloprotease domain, D: disintegrin-like domain, T1: the first thrombospondin type 1 repeat, C: Cys-rich domain, S: spacer domain, T2-8: the second to eighth TSP1 repeats, CUB: Complement c1r/c1s, sea Urchin epidermal growth factor, and bone morphogenetic protein, Fc: Fragment crystallizable.

    Journal: Frontiers in Pharmacology

    Article Title: Kinetic modeling of the plasma pharmacokinetic profiles of ADAMTS13 fragment and its Fc-fusion counterpart in mice

    doi: 10.3389/fphar.2024.1352842

    Figure Lengend Snippet: Diagrams depicting the structures of ADAMTS13, MDTCS, and MDTCS-Fc. The MDTCS fragment is a truncated form of ADMTS13 and consists of the M, D, T1, C, and S domains essential to cleave vWF multimers. MDTCS-Fc consists of MDTCS, an IgG1 type hinge, and an IgG4 type Fc harboring YTE mutations to improve the FcRn binding affinity. M: metalloprotease domain, D: disintegrin-like domain, T1: the first thrombospondin type 1 repeat, C: Cys-rich domain, S: spacer domain, T2-8: the second to eighth TSP1 repeats, CUB: Complement c1r/c1s, sea Urchin epidermal growth factor, and bone morphogenetic protein, Fc: Fragment crystallizable.

    Article Snippet: A human ADAMTS13 DuoSet ELISA kit (R&D systems, Minneapolis, United States) was used to measure the concentrations of MDTCS or MDTCS-Fc in the plasma samples collected from the mice receiving MDTCS or MDTCS-Fc.

    Techniques: Binding Assay